Nutrient Mist Reactor: a Remarkable New Approach to Grow Hairy Roots in Reactor

Hairy roots are genetically transformed roots and highly recommended sources for various secondary metabolites products. Artimisinin is one of them and frequently utilized as pharmaceutical drug for malaria impairment. Hairy roots are fragile tissue and very much sensitive in regarding to culture inside the bioreactor. Designing of bioreactor and optimising the acquired physical and chemical parameter is the promising approach in industry. To date a large number of various bioreactor has been designed i.e Trickle bed, Bubble column, Air lift, Fluidized and Nutrient mist reactor (NMR) for the biomass cultivation of hairy roots. All reactor has their significant characteristics to stimulate high growth rate of biomass and scaling up the metabolite production but apart from these, the main remarkable feature is adequate nutrient supply to growing biomass which is highly observed in nutrient mist reactor in which nutrient supply is facilitated in the form of small droplets (0.5-3μm) known as mist. Since mist reactor has been well studied and accepted as a suitable reactor for hairy root culture.